KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H2AFX
All Species:
19.7
Human Site:
T121
Identified Species:
39.39
UniProt:
P16104
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16104
NP_002096.1
143
15145
T121
A
V
L
L
P
K
K
T
S
A
T
V
G
P
K
Chimpanzee
Pan troglodytes
XP_520760
155
16635
T121
A
V
L
L
P
K
K
T
E
I
C
E
H
S
G
Rhesus Macaque
Macaca mulatta
XP_001090149
155
16475
T121
A
V
L
L
P
K
K
T
E
I
C
G
H
S
G
Dog
Lupus familis
XP_853256
242
25674
T220
A
V
L
L
P
K
K
T
S
A
T
V
G
P
K
Cat
Felis silvestris
Mouse
Mus musculus
P27661
143
15124
S121
A
V
L
L
P
K
K
S
S
A
T
V
G
P
K
Rat
Rattus norvegicus
P02262
130
14059
L109
T
I
A
Q
G
G
V
L
P
N
I
Q
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512371
142
15010
S121
A
V
L
L
P
K
K
S
G
A
A
S
S
P
K
Chicken
Gallus gallus
P02263
129
13922
V108
V
T
I
A
Q
G
G
V
L
P
N
I
Q
A
V
Frog
Xenopus laevis
Q6GM86
139
14837
L117
P
N
I
Q
A
V
L
L
P
K
K
S
S
G
G
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
T121
A
V
L
L
P
K
K
T
G
Q
A
A
A
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
I102
K
L
L
S
G
V
T
I
A
Q
G
G
V
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
Q105
L
S
G
V
T
I
A
Q
G
G
V
L
P
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
79.3
58.6
N.A.
97.1
85.3
N.A.
93
85.3
84.6
87.4
N.A.
79
N.A.
N.A.
81.8
Protein Similarity:
100
81.2
81.9
59
N.A.
99.3
86.7
N.A.
94.4
86.7
90.2
90.2
N.A.
83.2
N.A.
N.A.
84.6
P-Site Identity:
100
53.3
53.3
100
N.A.
93.3
0
N.A.
66.6
0
0
53.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
53.3
53.3
100
N.A.
100
6.6
N.A.
73.3
13.3
6.6
53.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
9
9
9
0
9
0
9
34
17
9
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
17
17
9
0
25
9
9
17
25
9
25
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
9
17
0
0
9
0
9
0
17
9
9
0
0
9
% I
% Lys:
9
0
0
0
0
59
59
0
0
9
9
0
0
0
34
% K
% Leu:
9
9
67
59
0
0
9
17
9
0
0
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
9
0
0
9
0
% N
% Pro:
9
0
0
0
59
0
0
0
17
9
0
0
9
34
9
% P
% Gln:
0
0
0
17
9
0
0
9
0
17
0
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
0
0
0
17
25
0
0
17
17
25
9
% S
% Thr:
9
9
0
0
9
0
9
42
0
0
25
0
0
0
0
% T
% Val:
9
59
0
9
0
17
9
9
0
0
9
25
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _